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Vacuum Dryers for APIs

Vacuum Dryers: The Easy Way of Drying APIs

| Author / Editor: Paolo Santi* / Manja Wühr

Concentric agitator detail
Concentric agitator detail (Picture: Massimo Forchino/Italvacuum)

Vacuum dryer system for API, fine chemicals and intermediates—Maximum ease of cleaning, maintenance and internal inspection even for multi-product applications: The horizontal paddle vacuum dryer by Italvacuum is the result of a deep analysis, conducted in cooperation with the most demanding operators, regarding the most urgent requirements of their production.

Power, loading flexibility, drying speed, ease of unloading, maximum product quality are all fundamental values of a vacuum dryer system. But Italvacuum went further, in order to facilitate cleaning and internal inspection. A quality that allows to maintain over time the machine’s perfect efficiency and to optimize the production processes.

The Cosmodry System is based on an operating philosophy conceived for the drying of wet powders coming from filtration or centrifugation stages and it is suitable for the production of Active Pharmaceutical Ingredients (API), Fine Chemical and Intermediates.

Constructive Details

This vacuum dryer system presents a great loading flexibility. It is manufactured in volumes ranging from 150 to 4.400 liters. The loading capacity can vary from 30 to 80 percent of the chamber’s volume, according to the processed product, meeting in this way the multiple needs of chemical and pharmaceutical industries.

The peculiar configuration of the agitator enables continuous stirring of the product and facilitates its thermal exchange, reducing drying time. Moreover, it was designed to limit mechanical and thermal stresses, thus allowing the treatment of thermo-sensitive products. But that is not all. Its special features allow to reduce product deposition at a minimum, providing an easy and efficient unloading operation, for which a dedicated operative cycle has been introduced.

Corrosion Resistant Material Selection

For the parts that are in contact with the product Cosmodry System is built in AISI 316L stainless steel, but other weldable materials are also available if requested by customer, for instance Alloy C-22 and AISI 904L.

The walls of the drying chamber, the port lid and the agitator shaft are heated through diathermic liquid circulation. Internal surfaces are mirror polished or electropolished in order to optimize resistance to corrosion, reduce friction on the product and simplify cleaning operations.

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