Dedicated Equipment From Comecer Preserves Isolation When Vials Are Filled

Related Vendors

DÜPERTHAL Sicherheitstechnik GmbH & Co. KG

Lutz Pumpen GmbH

Italvacuum, Srl

Comecer SpA

The three doors — two at the front and one at the back — carry viewing panels made from 12 mm tempered glass and have inflatable seals made of FDA-approved silicone.

Each door has two circular or oval glove ports fitted with Hypalon gloves. Optical sensors stop the machine if the operator inserts an arm during normal operation. There are two waste discharge ports for rejected vials, and two ports into which particle counters can be mounted.

The unidirectional air flow system is designed to be connected to a dedicated HVAC system. Filtration is by HEPA H14 filters with pressure transmitters to control the air pressure and activate an alarm when the differential pressure becomes too high.

The 304 stainless steel electrical panel has free contacts which can optionally be controlled by the PLC of the cap sealing machine.

Mouse hole

The mouse hole chamber acts as a buffer separating the crimping cabinet from the Class C environment of the surrounding laboratory. Its construction matches that of the crimping cabinet, with 3 mm thick 316 stainless steel, all welds ground and polished, a mirror-polished interior with 20 mm radii, and a Scotch-Brite external finish. There is a single door equipped with an inflatable silicone gasket, a viewing panel of 12 mm tempered glass, and a single port for a Hypalon glove.

Cap loading container

The cap loading container has room for around 3,000 aluminum caps, which are loaded through a door fitted with a viewing panel in 12 mm glass. The door has an inflatable gasket and a position sensor.

The container itself is made from 316L stainless steel, with a flange connecting it to the crimping cabinet. This connection is via a vertical sliding door actuated by a pneumatic cylinder, allowing the flow of caps to the crimping cabinet to be started and stopped as required. This door also has a position sensor and is interlocked with the filling door, so that whenever the latter is opened the door to the crimping cabinet closes.

(ID:22889500)