Guest Article
Taste Masking Coating of Multi-Particulate Systems in a Small Footprint Equipment

From Caterina Funaro, Ima Active Division, Competence Center Manager; Massimo Malavolti, Ima Active Division, Product Manager for Coating Equipment; Thorsten Cech, BASF, Manager European Pharma Application Lab 3 min Reading Time

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Ima Active’s wedge wire screen drum is designed to integrate seamlessly with standard Perfima equipment, resulting in the innovative Perfima Edge. This enhancement brings the capability of side vented pan coating to smaller particles, such as pellets or minitablets. The drum's wedge wires feature a rounded, smooth design, ensuring minimal impact on the product and enhancing flowability. The drum’s unique structure also supports high process air volumes, enabling increased spray rates and efficient, short processing times comparable to traditional perforated drum coaters and provides an interesting alternative to fluid bed thanks to its reduced footprint by at least 30 %.

Figure 1. Perfima Edge 30 L for 25 kg batch.(Source:  Ima)
Figure 1. Perfima Edge 30 L for 25 kg batch.
(Source: Ima)

When processing multi-particulate systems Perfima Edge (Figures 1-2) offers distinct benefits over fluid bed technology. Firstly, it requires markedly less space for equipment installation: for example, 25 kg batch in Perfima Edge requires 600 m3/h as processing air while in a fluid bed the required flow rate would be around minimum 800 m3/h. Secondly, it provides easy access to spray guns during operation. Furthermore, the drum coating process is easier to control, facilitating smoother up-scaling.

When selecting a coating technology, it is essential to prioritize both, the quality and cost-effectiveness of the process, along with space requirements. Factors such as processing time and the uniformity of the final product are crucial considerations too.