Salt tablets are used in various home care or chemical applications, like washing machines in households, hotels and restaurants or laundries. It can also be used for softening of drinking water, disinfecting swimming pools and also as nutritional supplements for animal nutrition.

Reig Jofre has entrusted Ima Life with the installation of its new line of sterile freeze-dried products, the largest and most modern in Spain. A complete, versatile, fully automated line designed to adapt to the manufacture of different products with the highest quality and in compliance with the new Annex 1 of the GMPs.

Recognised as the most stable and economic pharmaceutical forms, tablets are produced in general with an instant release (IR) formulation comprising 500 or 1000 mg of API content. This article aims to enhance the tableting production process.

Maintenance in automatic machines is usually addressed on a time basis. This means that parts are checked or substituted at regular time intervals or at a predetermined amount of working hours. This approach is called ‘pre-emptive maintenance’. An alternative approach, called ‘predictive maintenance’, suggests performing maintenance only when necessary.

Amidst the global pandemic of Covid-19, Ima will be organising a virtual ‘Sensing Future Days’ event from May 11–13 as well as from June 10–11 for the packaging industry. The participants can update themselves on the technical details of various machines showcased at the show and also interact with specialists from the field.

Collaboration, sharing experiences, and digital working are the keywords that feature Stay Connect!, the digital platform launched by Ima to enhance and offer all the Group’s digital products on a single touchpoint.

Schmelztabletten lösen sich im Mund und kombinieren die Vorteile fester und flüssiger Arzneimittelformen. Die Herausforderung bei direkt verpressten Schmelztabletten besteht darin, Rezeptur- und Herstellungsparameter zu finden, damit Tabletten mit geeigneter mechanischer Festigkeit und geringer Zerfallszeit entstehen. Worauf man bei der Formulierung und der Einstellung der Tablettierparametern achten sollte.

The coating of directly compressed mini-tablets in a pan has not been extensively utilised; however this process shows advantages over the fluid bed. The following study investigates the possibility of manufacturing a sustained release multiple dosage form by coating in a solid wall pan mini-tablets produced by direct compression.

Blending is an important process step in the manufacture of pills and other oral solid dosages. The latest FDA Guidelines focus particularly on a continuous verification of this process step. Learn more about monitoring the blend by means of NIR spectroscopy.

Das Homogenisieren von Feststoffen ist u.a. bei der Medikamentenproduktion relevant, wo die Wirkstoffe gleichmäßig in den einzelnen Tabletten verteilt sein müssen. Doch wie lässt sich der Zeitpunkt der vollständigen Homogenisierung bestimmen und der Mischprozess optimieren? Hier eignen sich Infrarotsonden und die statistische Versuchsplanung.