Software New Simca 16 Software for Multivariate Data Analytics

Editor: Ahlam Rais

The new software saves time with functionality, modelling and data pre-processing. It also makes model data easier to interpret for better process control and mines data to help optimise product quality, resource use and cost efficiency.

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Sartorius Stedim Biotech introduces new Simca 16 software for multivariate data analytics.
Sartorius Stedim Biotech introduces new Simca 16 software for multivariate data analytics.
(Source: Sartorius Stedim Biotech)

Sartorius Stedim Biotech (SSB) has recently announced that the new Simca 16 software for multivariate data analytics is available from its subsidiary Sartorius Stedim Data Analytics. The updated software focuses on delivering a complete data analysis experience, from data organisation through to data-driven decision making, supported by multivariate models for single and multiblock analysis.

According to the company, the new software has enhanced functionality features which will save time for expert users, as well as those new to multivariate data analysis. Usability improvements provide novices with an intuitive introduction to Simca and existing users with superior plot interactivity and quick raw data visualisation capabilities.

The software’s updated graphical interface with its context-based ribbons and panes means scientists will spend less time looking for functions and the new ribbons will be especially useful for those working with batch data. The new data analytics software also includes a wizard that adapts to users’ modelling objectives (rather than focusing on which algorithm to use) and guides them through set-up, making the initial steps of creating each model easier, states the firm. Additionally, its advanced data merging functionality saves time by eliminating the need to manually combine and align data in Excel.

To make pattern data in models easier to interpret and use, the new software comes with novel score space exploration and multivariate solver tools which help turn models into real-life factor combinations. In just one click, the score space exploration tool allows users to convert scatter plots into real factor settings for example, detect which sample is missing in a stack of observations, adds the firm.

With the multivariate solver tool, scientists can determine optimum factor settings for desired process outputs such as Critical Quality Attributes and can also lock model parameters to a specific batch of raw material to find the process parameters for achieving consistent product quality and operational efficiency. Both tools make trouble shooting process data and performing deviation analysis simpler tasks.

To increase application and functional flexibility, the new software includes Moca, a novel tool for analysing more than two blocks of data and new Python plugin capability. Moca provides a quick overview of an entire system, delivering invaluable information for continuing analysis, and is ideal for scientists such as systems biologists wanting to compare data from one system that has been obtained using different ‘omics’ and other techniques, mentions the company.

The Python plugin functionality in Simca 16 provides greater workflow flexibility by enabling users to create a file reader plugin which can read files like any other file format as they are being imported, adds the firm. This is especially useful when scientists need to transfer data from a new instrument with a non-standard export format or from text files where data is not configured correctly for Simca, saving them time and effort with pre-processing and importing data.

“Developing and producing biotherapeutics generates a vast array of process data in different formats from a variety of equipment types. This data holds the key to improving performance but can be challenging to input, model and interpret,” said Stefan Rännar, Product Manager at Sartorius Stedim Data Analytics. “We’re pleased to introduce our new software because it offers elevated levels of control over data, model generation and decision making, enabling scientists to optimise resource use and cost efficiency, while more importantly, achieving consistency in their product quality,” he added.

The use of Simca is recognised by the EMA and US FDA for real-time release testing and the Simca 16 software has been developed and extensively tested and validated for use in a highly-regulated environment, states the company.