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Diaphragm Pumps The Right Pump Helps to Optimize Radial Flow Chromatography

Editor: Dominik Stephan

Getting down to the lab: Quattroflow's new single-use quaternary diaphragm pumps are perfectly suited for Radial Flow Chromatography (RFC) systems. RFCs are typically used in biopharmaceutical productions to adsorb and purify Active Pharmaceutical Ingredients (API).

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Quattroflow pumps are available in QF-150, QF-1200, QF-4400, QF-5050 and QF20K sizes
Quattroflow pumps are available in QF-150, QF-1200, QF-4400, QF-5050 and QF20K sizes
(Picture: Quattroflow)

The typical chromatography-column design is “axial,” wherein the chromatographic media is packed in a flat cylinder that is both heavy and space-consuming. RFC on the other hand, orients the chromatography cylinder vertically with the media around it, reducing both the system’s footprint and weight while maintaining the high level of purification. Quattroflow pumps are perfectly suited for this application because their four-piston/four-diaphragm–design and operation delivers low pulsation, gentle product handling, a large turndown ratio, high flow-rate accuracy, low noise and a compact construction.

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