Top–Trend Single–Use Bioreactors: Hype or Gamechanger for Bioprocesses?

Related Vendors

Glatt Ingenieurtechnik GmbH

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TRM Filter d.o.o.

Sartorius AG

Potentials for Further Development in Single–Use Bioreactor Technologies

PROCESS:

What are the R&D areas that you are concentrating on?

JORNITZ:

See, R&D is driven by customers and not by Sartorius internally. Taking the example of single-use technology again, there is a high demand from our clients to bring single-use technology not only into the up-stream side, for example fermentation but also into the downstream process steps for example in purification technologies. Here again we work on new innovative membrane chromatography systems to reduce processing time and resources.

We also believe that the industry is looking for standardisation of contact layers, the polymeric film that comes in contact with the products, but flexibility of the film laminates. More work needs to be done in this

area, but we see progress to fulfill future requirements.

New Trends for Single–Use Technology

Then from critical processing step, the sterilising grade filtration area, we will launch very shortly next generation sterlising grade filters, which is called Sartopore Platinum, a unique high performance filter.

Another area that we are currently working on is the prefilters to protect sterilising grade filters and viral filters. We need to have new pre-filtration strategies, so, we are looking into nano-fibre technologies – and we will launch nano-fibre pre-filters, which have a much more tightened contaminant separation and total throughput capacity.

The G–Con: Sartorius' New Development

We again have another innovative system, which we are bringing out with our alliance with G-Con. This is the company that produces flexible production modules which include independent air handling systems and utility connectivity. They can be utilised as flexible production areas with their own clean room capacities. We believe this will be the really innovative and groundbreaking technology – when it comes to new production designs and new production facilities.

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