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Continous Granulating and Drying Developement of Continous Twin-screw Granulation and Drying Solutions

| Editor: Dominik Stephan

ThermoFisher Scientific and Glatt jointly develop a continous twin-screw granulator and drier for pharmaceuticals to provide a one-step solution for the whole manufacturing process from powder handling to tablet production.

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Twin-screw granulator Pharmalab 16 by ThermoFisher. The company recently announced to jointly develop a continous granulator/dryer together with Glatt using the companies proven continous drying technology. (Picture: ThermoFisher)
Twin-screw granulator Pharmalab 16 by ThermoFisher. The company recently announced to jointly develop a continous granulator/dryer together with Glatt using the companies proven continous drying technology. (Picture: ThermoFisher)

Many pharmaceutical companies still rely on batch processes to manufacture high grade products. Nevertheless, the interest in continuous processing increases as manufacturers try to reduce manufacturing costs and improve performance.

“To improve performance and yield in production processes, pharmaceutical companies are increasingly adopting continuous processing, especially for granulation,”, said Markus Schreyer, vice president and general manager of the Thermo Fisher Scientific’s material characterization business. “Our customers have confirmed that twin-screw granulation is the next step in continuous processing because it simplifies scale-up, and we’re able to offer a comprehensive twin-screw granulation portfolio to meet their specific needs, from research and development to production.”

Thomas Hofmaier, head of Glatt’s pharma process technologies business unit, expects synergetic effects for both the companies and customers: “Glatt already serves customers using continuous process technologies in the food, feed and fine chemical sectors, and the pharmaceutical industry is next for this innovation. Combining Thermo Scientific twinscrew granulation technology with Glatt’s continuous drying technologies, as well as our complementary expertise in system integration and applications, offers a unique and beneficial solution to our customers.”

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