Innovations on Display Complete Process Solutions at Achema

Related Vendors

Korsch AG

Angst + Pfister AG

Glatt Ingenieurtechnik GmbH

Italvacuum, Srl

Korsch, its affiliate Medelpharm and L.B. Bohle will be presenting their solutions at the soon to be held Achema 2024 event in Frankfurt am Main, Germany in a shared booth in hall 3, booth A49 / A71.

A highlight of the Korsch display will be the recently introduced X 5 advanced single sided tablet press, which raises the benchmark for manufacturing efficiency, with significantly higher output capability than comparable machines on the same footprint. This is achieved by leveraging the Korsch trademark ergonomic fast-change design with a newly engineered turret execution with segments.

For example, the standard B turret with conventional dies has 43 punch stations, and the segmented execution offers 54 punch stations, which represents a 25 % increase in machine output.

The X 5 comes in two versions: the X 5 SFP provides dedicated single-layer capability, while the X 5 MFP offers single-layer, bi-layer, and tri-layer flexibility.

Both models share a common turret and interchangeable product contact parts for maximum efficiency and flexibility in high-speed, high-volume production environments. Incorporating Korsch’s latest innovations, the X 5 features an integrated electrical cabinet, torque drive, fully sealed design, and unsurpassed accessibility for cleaning, changeovers, and maintenance, shares the company. Installation options include through-the-wall mounting.

Also on display will be the mid-range X 3 tablet press that incorporates production capabilities and versatility traditionally limited to large-scale production machines. The tablet press is a single-sided rotary press that redefines the market segment for presses suitable for product development, scale-up, clinical production, mid-range production and continuous manufacturing, adds the firm.

The tablet press shows why it won the 2022 Pharma Innovation Awards with advanced technologies and features that include a fully integrated control cabinet, exchangeable turret configuration to offer unprecedented flexibility and production adaptability, the capability for fully instrumented measurement of precompression, main compression, or ejection forces, and unsurpassed accessibility for cleaning, changeovers and maintenance. The X 3’s optional integrated data acquisition system permits full characterization and documentation of scale-up parameters.

The X 3 tablet press is available in two models, with the X 3 SFP accenting high speed production at up to 266,400 tablets/hour while the X 3 MFP places the emphasis on flexibility between single-layer and bi-layer capabilities.

Korsch will also show its XT 600 high speed double rotary press that combines:

Key features from proven Korsch technology with a simple, modular, and cost-efficient design to offer a new standard in high-volume production equipment. Like all Korsch tablet presses, the XT 600 features a control system interface that combines an intuitive HMI environment with an unprecedented level of on-line help and assistance to advise the user in every aspect of the machine operation. A 19-inch touch screen display supports gestures to permit move, zoom, and scroll functions to simplify and enhance the user experience, mentions the company. The design has not only been focused on a high output but also on operator convenience. Leveraging the unique and patented carrier plate concept from the XL-series, the XT 600 features the same market leading noise reduction technology.

The Achema stand will also feature a tableting R&D laboratory equipped with one of the industry’s most advanced product lines for OSD material characterization, feasibility assessment, formulation development and scale-up. The Achema Lab will feature live demonstrations of the Medelpharm Styl’One range of compaction simulators, including the benchtop Styl’One Nano and the Styl’One Evo.

The Styl’One Evo can claim to be the most advanced and versatile compaction simulator in the world, allowing researchers to replicate any high-speed production press

with unlimited flexibility to explore single-layer, multi-layer, and tablet-in-tablet formats, opines the firm. A GMP production module permits the production of small technical batches including weight regulation, tablet sorting, and batch report. A multitude of options and features can be selected including dry granulation mimicking module, radial die pressure measurement, automatic external lubrication units, etc.

Meanwhile, the ultra- compact Styl’One Nano provides an ideal tool to develop formulations using small material quantities. An integrated data acquisition and analysis system offers a simple and powerful tool for material characterization, while its unique drive system permits a range of standard compression profiles, including the ability to replicate precompression and main compression on a small rotary tablet press, concludes the company.

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