Granulation A Compact Granulation Unit Keeps Things Running Smoothly

Editor: Dr. Jörg Kempf

Granulation has often been plagued by blocked transfer lines, the difficulty of having to operate the system at multiple levels and time-consuming cleaning. A new granulation unit sets new standards in wet granulation.

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Control after cleaning: It takes less effort to clean the system, which is a significant advantage that not only contract manufacturers will appreciate. (Picture: Bohle)
Control after cleaning: It takes less effort to clean the system, which is a significant advantage that not only contract manufacturers will appreciate. (Picture: Bohle)

When a wet granulator and fluidized bed dryer are installed on the production floor, the complete system often extends over several levels. L.B. Bohle has developed a new granulating unit featuring a very compact design.

The wet granulator and fluidized bed dryer with intermediate screening stage take up minimal space. The reduction in footprint and height eliminates the need to extend the system up through the concrete ceiling in many production areas. The design of the filtration unit drive subsystem in the Bohle BFS (fluidized bed system) reduces the overall height of the granulator. The long pneumatic cylinders, which normally protrude well above the actual process chamber on this type of system, have been eliminated. The height of the inlet plenum has also been reduced.

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Optimal Airflow

The new flat, tangential air inlet ensures optimal airflow through the distributor plate in the product chamber. The multi-function valve is positioned low down for easy charging and discharging. With this design, there is no need for a platform to provide operator access at two levels. As a result, it takes less effort to clean the system, which is a significant advantage that not only contract manufacturers will appreciate.

“The very compact, space-saving design is the outstanding feature of the compact system. It fit easily into our production facility without the need for any major modifications to the building,” commented Dr. Michael Beyer, Production & Engineering Manager at Wiewelhove, in describing the key advantage of the Bohle granulator.

The company is a pharmaceutical contract manufacturer and the first customer for the compact system. Dr. Beyer is also impressed with the short product transfer paths between the mixer and the fluidized bed subsystem. The low positioning of the tube mounted at a slight gradient which transfers the screened wet granulate to the BFS is ideal from the ergonomic point of view, and it also has significant process engineering advantages. The section of tube is extremely short, straight and smooth. This solution along with the multi-purpose valve ensures unobstructed product transfer without any fittings or redirection which would obstruct the flow.

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