New Capsule Solution for Intestinal Drug Delivery

Pharma Innovations New Capsule Solution for Intestinal Drug Delivery

2022-12-19 Source: Press release Ahlam Rais

Related Vendors

Lonza Ltd.

EagleBurgmann Germany GmbH & Co. KG

Glatt Ingenieurtechnik GmbH

ProMinent GmbH

Lonza has introduced ‘Capsugel Enprotect’ which is the first ever coating-free capsule which supports intestinal delivery of acid-sensitive APIs. This new capsule technology has the potential to make significant improvements to oral drug delivery.

Lonza's capsule meets a pressing market need for an effective oral delivery solution for treatments that are easily degraded by acidic stomach conditions. (Source: Lonza) — Lonza's capsule meets a pressing market need for an effective oral delivery solution for treatments that are easily degraded by acidic stomach conditions.
(Source: Lonza)

Lonza has launched an innovative new capsule solution for intestinal (enteric) drug delivery. The Capsugel Enprotect capsule does not disintegrate during stomach transit and only releases its contents in the intestine. Capsugel Enprotect capsules significantly simplify the drug product manufacturing process by mitigating the need for additional capsule coating or sealing. This most recent capsule innovation has delivered a breakthrough non-coated capsule for enteric delivery that is suitable for all stages of development and commercial supply, states the company.

The capsule meets a pressing market need for an effective oral delivery solution for treatments that are easily degraded by acidic stomach conditions. The new delivery solution targets small molecules, peptides, proteins, and RNA-based therapeutics. It will also help to enable the delivery of live biotherapeutic products, a new and innovative class of treatments.

This new capsule technology has the potential to make significant improvements to oral drug delivery. With its proven protection in acidic environments, Capsugel Enprotect provides drug developers with a viable oral solution to deliver novel therapies to the distal small intestine, including live biotherapeutic products, small and large molecules, and oral vaccines, concludes the firm.

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