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Melt Extrusion Improves Bioavailability of Low-solubility Active Agents

Bioavailability of felodipine, an active agent used in treating high blood pressure. The active agent in its pure form (white circles) cannot be detected in the plasma in contrast to the extruded form (grey circles). (Source: Prof. Duncan Craig, University of East Anglia) (Archiv: Vogel Business Media) arrow forward Image Zoom
Bioavailability of felodipine, an active agent used in treating high blood pressure. The active agent in its pure form (white circles) cannot be detected in the plasma in contrast to the extruded form (grey circles). (Source: Prof. Duncan Craig, University of East Anglia) (Archiv: Vogel Business Media)
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