Every Drop Counts when Bulk Filling Drug Substance

Smart Solutions Every Drop Counts when Bulk Filling Drug Substance

2024-09-20 Source: Press release Cytiva 1 min Reading Time

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The Allegro Connect bulk fill system from Cytiva has been designed to help you reduce non-recoverable product loss by up to 50 %.

The system has been designed to automate product draining and recovery within both the filtration and distribution flow paths.(Source: Cytiva) — The system has been designed to automate product draining and recovery within both the filtration and distribution flow paths.
(Source: Cytiva)

Minimizing non-recoverable volume at the end of drug substance downstream processing is critical for efficient product recovery. With manual processes and complex single-use paths this can be difficult to achieve.

The Allegro Connect bulk fill system has been designed to help you reduce non-recoverable product loss by up to 50 %, shares the company.

Here are some ways this is possible:

The system has been designed to automate product draining and recovery within both the filtration and distribution flow paths

The single-use flow path used has a compact design and is easy to use, allowing maximum product draining

Efficient use of fluid in the recovery biocontainer bag allows ability to re-dispense into the final filling containers

Three model process scenarios have been selected to give end users an indication as to non-recoverable hold-up expected within the flow path, based on varied process requirements and volumes.

The Allegro Connect bulk fill system minimizes process risk through increased automation, and has been designed for enhanced configurability allowing flexibility and choice for multiple processes, adds the firm.

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