Software PSE Releases Major Update of gSOLIDS for Solids Process Design and Operation

Editor: Dominik Stephan

Process Systems Enterprise (PSE), the Advanced Process Modeling company, has announced the release of 'Gsolids' 3.0, an integrated drag & drop graphical flowsheeting environment for process engineers and scientists in industries where particulate processes play an integral part, such as pharmaceuticals, fine chemicals, agrochemicals, food processing, consumer goods and minerals and mining.

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PSE Releases Major Update of gSOLIDS for Solids Process Design and Operation
PSE Releases Major Update of gSOLIDS for Solids Process Design and Operation
(Picture: PROCESS)

London/United Kingdom – Gsolids 3.0 extends existing capabilities for drug product manufacturing with new tableting unit operation models for compaction, coating and in-vitro testing, all of which were developed in close collaboration with pharmaceutical clients. Other new models include an electrostatic precipitator, a dynamic screen model, a fluid bed agglomerator and an agglomerator that incorporates breakage models.

The new version brings significant improvements in speed and robustness. It also includes usability improvements in the form of an expanded set of sensor and control models which include holdup and stream sensors for reporting moisture content and particle size distribution (PSD) as volume density distributions and quantiles, as well as a PSD monitor that allows comparison of size distributions from different sensors. New facilities have been added for easy creation of operating procedures for batch processes.

Similarly to previous Gsolids releases, version 3 was developed in close collaboration with clients such as AstraZeneca, Novozymes, Pfizer and Procter & Gamble. A key advantage of Gsolids is that it is built on PSE’s gPROMS advanced process modelling platform, which provides the ability to perform full steady-state and dynamic modelling, handle large numbers of recycles robustly, model complex operating procedures for batch and semi-continuous processes, and easily add custom models to reflect users’ actual unit operations. It can also handle multiple solid phases, each with its own particle size distribution and size dependent composition.

Sean Bermingham, VP of PSE’s Solids strategic business, says “The ability to handle dynamics – essential for batch process optimization – as well as combine models and experimental data using population balance models, perform rigorous optimization on large problems, and implement custom models rapidly, makes gSOLIDS unique in the solids processing industries. Our ModelCare service also helps customers achieve results rapidly”.