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Flow Chemistry Going with the Flow: Flow Chemistry Pavilion

Editor: Dr. Jörg Kempf

According to nature.com, “Flow chemistry is the development and study of chemical reactions whereby reactants are combined by pumping fluids, including solutions of reagents, through tubes at known rates. The relative proportions of the reactants are controlled by their concentrations and relative flow rates.

Within the pharmaceutical indus­try, there is a shift away from blockbusters towards lower volume, higher potency API’s — an opportunity for manufacturers to adopt newer methods of production.
Within the pharmaceutical indus­try, there is a shift away from blockbusters towards lower volume, higher potency API’s — an opportunity for manufacturers to adopt newer methods of production.
(Bild: ©MG - stock.adobe.com)

These reactions can take advantage of rapid mixing and surface to volume ratio effects.” Furthermore, rapid process optimisation, faster reactions, cleaner products, increased safety and ease of scale-up and additional advantages can be gained by integrating unit operations such as work-up and analysis. Flow chemistry enables the production of synthetic intermediates and products that would otherwise be inaccessible using conventional batch techniques.

Specifically, within the pharmaceutical industry, as the “patent cliff” looms for many high-volume API’s, there is also a shift away from blockbusters towards lower volume, higher potency API’s. This presents an opportunity for manufacturers to adopt newer methods of production — one answer being continuous manufacturing — a trend that cannot be ignored anymore. The Flow Chemistry Pavilion provides visitors with a unique one-stop opportunity to get an in-depth introduction into this increasingly important manufacturing topic. Alongside the presentations and discussions there is an exhibition area highlighting the tools available to leverage the benefits of flow chemistry, responding to an increasing demand for adaptability and resource efficiency within the chemical manufacturing landscape.

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