Contained Milling Facility API Particle Size Reduction Facility
Hosokawa developed a contained particle size reduction facility that is suitable for flexible milling down to ultrafine particles of active pharmaceutical ingredients at R&D, pilot scale and small scale production volumes. The contained API particle size reduction facility includes three mills plus a lump breaker, three material feed options and operator exposure levels of <1µg/m3. Manufactured to cGMP design and incorporating full Scada control the system consists of two separate but interconnecting isolator chambers, the milling chamber and the product collection chamber. Product feed and mill placement is at the rear of the unit. Production operatives work from the front of the unit.